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Recent Articles

The Simultaneous Activation of Nrf2 and Antioxidant Compounds may reduce the Risk, Progression, and Improve the Management of Diabetes by Reducing Oxidative and Inflammatory Damages

Despite extensive research, the incidence of diabetes continues to increase, and the management of diabetes needs improvement, because in 2016, more than 100,000 patients had lower extremity amputated, suffered ischemic heart disease and stroke. Analysis of investigations indicates that increased oxidative stress and chronic inflammation enhance the risk, progression, diabetic–related complications, and reduce effectiveness of drug therapy. Therefore, simultaneously attenuation of these cellular abnormalities may help in reducing the risk of development, progression, and prolonging the effectiveness of drug therapy.

Liquorice-Induced Pseudohyperaldosteronism with Severe Hypokalaemia in a Young Patient Living with HIV: A Rare Case Presentation and Literature Review

HIV-1 infection treatment has greatly improved with the availability of combined antiretroviral therapy (cART). Unlike Tenofovir Disoproxil Fumarate, Tenofovir Alafenamide has a more favourable renal profile, even if proximal tubulopathy and electrolyte disturbances have been reported. As earlier as 4000 years ago, liquorice root was used for some medical treatments. Excessive liquorice intake is described to cause a state of mineralocorticoid excess. However, liquorice-induced hypokalaemia usually occurs with mild clinical manifestations and a severe presentation is rare.

Soybean Lecithin-Based Extender Improves the Quality of Chilled Canine Sperm

Semen preservation technique includes chilling at 4-5 oC and cryopreservation at -196 oC. The role of extender enriched with protectant is essential for storing sperm. In order to evaluate the effects of different concentrations of soybean lecithin (SL) in Tris-based extender on quality parameters of chilled canine semen and subsequent potential. The Trisbased extenders with 0.5%, 1.0% or 2.0% SL (w/v) were used to store the sperm of French Bulldog; meanwhile, Tris-based extenders supplemented with 20.0% (v/v) egg yolk (EY) were used as the control group. Sperm samples in each group were stored at 4⁰C for 168 hours period.